Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC547H888N154O166S3

DescriptionStandard

        ADLTGHEKFGLGNVKYNISGIHITAVELPSASISLLPQSGIKLVIRNASLTINMNWNIRTWMFKDSGRSTVHISKVFVTAIFSTPQDNAGPTSISLTSCRTTSGDIDIKLNRKS
    

Molecular Weight12374.03 Da

Isoelectric Point (pI)9.80

Net Charge (pH 7.0)5.05

Net Charge (pH 7.4) 4.68

Charge Density (pH 7.0) 0.0443

GRAVY Index-0.04

Hydrophobic Moment 0.59

Boman Index0.08

Instability Index41.06

Aliphatic Index 95.79

Aromaticity 0.0614

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5163.93

LogP -60.04

H-bond Donors 183.0

H-bond Acceptors 177.0

Rotatable Bonds 412.0

Heavy Atoms 870.0

Ring Count 16.0

Amide Bonds 123.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0047632 VERIFIED: NO

Provenance & Taxonomy

OrganismScytalopus superciliaris [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria