Peptide Database

Peptide NameCathelicidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length173 amino acids

Chemical FormulaC844H1387N241O251S8

DescriptionStandard

        MGTMKTQRDGPSLGRWSLVLLLLGLVMPLAIVAQVLSYQEAVLRAIDGINQRSSDANLYRLLDLDPRPTMDGDPDTPKPVSFTVKETVCPRTTQKSPEDCDFKEDGLVKRCVGTVILNQARDSFDISCDKDNRKFARLGNFFRKVKEKIGGGLKKVGQKIKDFLGNLVPRTAS
    

Molecular Weight19183.03 Da

Isoelectric Point (pI)9.36

Net Charge (pH 7.0)6.48

Net Charge (pH 7.4) 6.16

Charge Density (pH 7.0) 0.0374

GRAVY Index-0.34

Hydrophobic Moment 0.75

Boman Index-0.08

Instability Index26.26

Aliphatic Index 88.96

Aromaticity 0.0578

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7979.94

LogP -89.67

H-bond Donors 279.0

H-bond Acceptors 266.0

Rotatable Bonds 651.0

Heavy Atoms 1344.0

Ring Count 21.0

Amide Bonds 185.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0079907 VERIFIED: NO

Provenance & Taxonomy

OrganismMandrillus leucophaeus [Animal]

FamilyCathelicidin family

Tax ID9568

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0086797 VERIFIED: NO