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MYP_012295
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Basic Information
Rhesus theta-defensin 3 (RTD-3; primates, mammals, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiviral
Standard
18 amino acids
C84H140N30O21S6
Standard
Sequence
RCICTRGFCRCICTRGFC
Physicochemical Analysis
2098.59 Da
9.01
3.70
3.41
0.2056
0.52
0.64
-0.13
36.23
43.33
0.1111
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
846.08
-10.13
39.0
31.0
67.0
141.0
2.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0021237 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Defensin
9544
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antiviral
Escherichia coli ML35
PaperPubMed PMID: 10521339 | PubMed PMID: 1152799 | PubMed PMID: 11675394 PMID10521339;1152799;11675394 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10521339/
RECORD: Rec_0028203 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Defensin
9544
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antiviral
Cryptococcus neoformans 271A (the activity of RTD-2 against Escherichia coli ML35 was 2-3-fold less than those of RTD-1 and RTD-3)
PaperPubMed PMID: 10521339 | PubMed PMID: 1152799 | PubMed PMID: 11675394 PMID10521339;1152799;11675394 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10521339/
RECORD: Rec_0046850 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Defensin
9544
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antiviral
Staphylococcus aureus 502a
PaperPubMed PMID: 10521339 | PubMed PMID: 1152799 | PubMed PMID: 11675394 PMID10521339;1152799;11675394 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10521339/
RECORD: Rec_0160241 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0222504 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Defensin
9544
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antiviral
Listeria monocytogenes
PaperPubMed PMID: 10521339 | PubMed PMID: 1152799 | PubMed PMID: 11675394 PMID10521339;1152799;11675394 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10521339/
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