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MYP_012293
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Basic Information
Pseudhymenochirin-2Pa
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
27 amino acids
C135H230N34O34
Standard
Sequence
GIFPIFAKLLGKVIKVASSLISKGRTE
Physicochemical Analysis
2873.48 Da
10.46
3.76
3.55
0.1394
0.65
0.69
0.23
9.02
130.00
0.0741
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1095.33
-7.43
39.0
38.0
99.0
203.0
3.0
26.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0000743 VERIFIED: YES
Provenance & Taxonomy
Pseudhymenochirus merlini [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa ATCC 27853
80 μM
MIC
PMID24212286;25447194;26606380 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24212286/
RECORD: Rec_0008602 VERIFIED: YES
Provenance & Taxonomy
Pseudhymenochirus merlini [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human colon adenocarcinoma HT29
11.5
LC50
PMID24212286;25447194;26606380 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24212286/
RECORD: Rec_0016826 VERIFIED: YES
Provenance & Taxonomy
Pseudhymenochirus merlini [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
HUVEC
68 μM
LC50
PaperCharacterization of the host-defense peptides from skin secretions of Merlin's clawed frog Pseudhymenochirus merlini: Insights into phylogenetic relationships among the Pipidae
RECORD: Rec_0022072 VERIFIED: YES
Provenance & Taxonomy
skin secretions of the frog Pseudhymenochirus merlini [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
A549
6±0.6 μM
LC50
PaperPubMed PMID: 25447194 PMID25447194 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25447194/
RECORD: Rec_0022965 VERIFIED: YES
Provenance & Taxonomy
Pseudhymenochirus merlini [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli ATCC 25726
40 μM
MIC
PMID24212286;25447194;26606380 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24212286/
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