Peptide Database

Peptide NameCyclotide Viphi E

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC134H217N35O42S6

DescriptionStandard

        CGESCVFIPCISAVIGCSCSNKVCYKNGSIP
    

Molecular Weight3182.76 Da

Isoelectric Point (pI)7.77

Net Charge (pH 7.0)0.70

Net Charge (pH 7.4) 0.40

Charge Density (pH 7.0) 0.0226

GRAVY Index0.72

Hydrophobic Moment 0.31

Boman Index0.26

Instability Index27.82

Aliphatic Index 81.61

Aromaticity 0.0645

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1215.64

LogP -15.37

H-bond Donors 47.0

H-bond Acceptors 49.0

Rotatable Bonds 100.0

Heavy Atoms 217.0

Ring Count 4.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0025038 VERIFIED: NO

Provenance & Taxonomy

OrganismViola philippica [Plant]

FamilyCyclotide

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Cytotoxic

TargetCancer cell line

RECORD: Rec_0304346 VERIFIED: YES