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MYP_012257
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Basic Information
U4
Antimicrobial
Antiviral
Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza A ▸ Anti-Influenza A virus
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Standard
21 amino acids
C101H149N33O29S2
Standard
Sequence
FINGRWDSQCHRFSNGAIACA
Physicochemical Analysis
2353.60 Da
8.08
0.83
0.55
0.0395
-0.21
0.57
0.01
69.64
51.43
0.1429
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1020.62
-12.45
38.0
33.0
74.0
165.0
5.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0096215 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PMID35259078 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35259078/
RECORD: Rec_0118249 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-Influenza A virus Replication inhibition
Influenza A virus (H1N1) | MDCK cells
2.804 μM
IC50
Mammalian: 1.1 h; Yeast: 3 min; E. coli: 2 min
PaperFusion-inhibition peptide broadly inhibits influenza virus and SARS-CoV-2, including Delta and Omicron variants. | Zhao H, Meng X, Peng Z, Lam H, Zhang C, Zhou X, Chan JF, Kao RYT, To KK, Yuen KY. | Emerg Microbes Infect. 2022 Dec;11(1):926-937. | DOI:10.1080/22221751.2022.2051753 | PMID:35259078 PMID35259078 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35259078/
RECORD: Rec_0193170 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Ponericin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
H1N1
PMID35259078 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35259078/
RECORD: Rec_0240910 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
influenza A virus(H1N1):inhibition of viral replication in MDCK cells
6.6 μg/mL
IC50
PMID35259078 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35259078/