Peptide Database

Peptide NameIbritumomab tiuxetan

Function Ontology

Anticancer

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Immunology ▸ Immunomodulation ▸ Immunosuppressive

Standard StatusStandard

Sequence Length652 amino acids

Chemical FormulaC3191H4916N836O990S27

DescriptionStandard

        QAYLQQSGAELVRPGASVKMSCKASGYTFTSYNMHWVKQTPRQGLEWIGAIYPGNGDTSYNQKFKGKATLTVDKSSSTAYMQLSSLTSEDSAVYFCARVVYYSNSYWYFDVWGTGTTVTVSAPSVYPLAPVCGDTTGSSVTLGCLVKGYFPEPVTLTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVTSSTWPSQSITCNVAHPASSTKVDKKIEPRGPTIKPCPPCKCPAPNLLGGPSVFIFPPKIKDVLMISLSPIVTCVVVDVSEDDPDVQISWFVNNVEVHTAQTQTHREDYNSTLRVVSALPIQHQDWMSGKEFKCKVNNKDLPAPIERTISKPKGSVRAPQVYVLPPPEEEMTKKQVTLTCMVTDFMPEDIYVEWTNNGKTELNYKNTEPVLDSDGSYFMYSKLRVEKKNWVERNSYSCSVVHEGLHNHHTTKSFSRQIVLSQSPAILSASPGEKVTMTCRASSSVSYMHWYQQKPGSSPKPWIYAPSNLASGVPARFSGSGSGTSYSLTISRVEAEDAATYYCQQWSFNPPTFGAGTKLELKRADAAPTVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFN
    

Molecular Weight71695.93 Da

Isoelectric Point (pI)7.83

Net Charge (pH 7.0)2.78

Net Charge (pH 7.4) 1.50

Charge Density (pH 7.0) 0.0043

GRAVY Index-0.36

Hydrophobic Moment 0.60

Boman Index0.03

Instability Index47.00

Aliphatic Index 68.25

Aromaticity 0.0997

Extinction Coeff. Reduced 123190.00

Extinction Coeff. Oxidized 124190.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0254665 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]; Cricetulus griseus [Animal]

FamilyRadiolabeled monoclonal antibody

Tax ID10090;10029

Structure & Mods

Configlinear multidomain protein biologic [Linear]

Chiralitynoncanonical stereochemical or chemical modification [Modified]

Other ModsTiuxetan chelator conjugation

Bio-Activity Profile

Function

Anticancer Immunomodulatory Immunosuppressive Monoclonal antibody

Half-Life0.8 h