Peptide Database

Peptide NameDefensin Ec-AMP-D2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC365H579N101O110S13

DescriptionStandard

        MDRSYRSVLVAFLLLSFLLATEMGPMSAEAKTCETQSGKFKGMCMSSTNCASVCKSEPGFDGGYCRGFRRQCFCTKPC
    

Molecular Weight8558.96 Da

Isoelectric Point (pI)8.70

Net Charge (pH 7.0)3.43

Net Charge (pH 7.4) 3.08

Charge Density (pH 7.0) 0.0439

GRAVY Index-0.05

Hydrophobic Moment 0.62

Boman Index0.00

Instability Index52.71

Aliphatic Index 47.56

Aromaticity 0.1026

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3394.00

LogP -39.82

H-bond Donors 129.0

H-bond Acceptors 127.0

Rotatable Bonds 284.0

Heavy Atoms 589.0

Ring Count 11.0

Amide Bonds 80.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0413471 VERIFIED: YES

Provenance & Taxonomy

OrganismGossypium australe [Plant]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicidal Non-hemolytic Non-ribosomal