Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length486 amino acids

Chemical FormulaC2392H3785N607O705S16

DescriptionStandard

        MFLWFVLVLVNLVSVATGTNAGVKVRLTQKGLEYGRQIGIASIQQKLRTIKVPDISGTETVDPIGKVQYSFTGMQIVNLGLPKSALGLVPDTGVMLSIGNGYINLHGNWRVKYLRIIKDSGSFDLAVSELTISTTIAVTNDDTGHPTVSMTNCAATVGSVNVKFHGGASWLYNLFSSFINKALCNALQKQICPLVADSSADINPHLKTLNVLAEVDQYAEIEYSMVGSPVISNTSIDLGLKGEFYNIGEHKEPPFSPIPFSFLSQDTDMIYIGVSAFTINSAGFVYNRAGALRLYITDDMIPSGSPIRLNTKTFGTFIPQIEKMYPGLMMKLLVETVKEPLITFEPNNVTVQASSTVTAYAIQPNSTLSPLFVLNLEGSVSTHIYVTELKLAGNMTLNKIDISLAKSYVGPFQVTSLDSIFTIVLKVAVIPKVNAHLQEGYPLPAIGKMQLVNSRQTEVVQVFGSFNCDDFGSHLTKTHQFTISTN
    

Molecular Weight52839.32 Da

Isoelectric Point (pI)6.51

Net Charge (pH 7.0)-1.73

Net Charge (pH 7.4) -2.56

Charge Density (pH 7.0) -0.0036

GRAVY Index0.19

Hydrophobic Moment 0.68

Boman Index0.19

Instability Index26.27

Aliphatic Index 102.22

Aromaticity 0.0864

Extinction Coeff. Reduced 40340.00

Extinction Coeff. Oxidized 40590.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0066204 VERIFIED: NO

Provenance & Taxonomy

OrganismCyprinus carpio [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria