Peptide Database

Peptide NamePaneth cell-specific alpha-defensin 22

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length100 amino acids

Chemical FormulaC461H758N150O141S8

DescriptionStandard

        MRTLALLAALLLLAFHAQAEPLGEKDDQVPAQDQPGADVQGMTISFEGDERSTRDAAGSRPGLICHCSSFCQRPHKQEGICTRGKLKRLCCRPDGRRGPR
    

Molecular Weight10914.39 Da

Isoelectric Point (pI)8.65

Net Charge (pH 7.0)2.72

Net Charge (pH 7.4) 2.25

Charge Density (pH 7.0) 0.0272

GRAVY Index-0.54

Hydrophobic Moment 0.62

Boman Index-0.16

Instability Index44.12

Aliphatic Index 70.40

Aromaticity 0.0300

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4685.01

LogP -55.48

H-bond Donors 168.0

H-bond Acceptors 155.0

Rotatable Bonds 365.0

Heavy Atoms 760.0

Ring Count 13.0

Amide Bonds 106.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0277430 VERIFIED: YES

Provenance & Taxonomy

OrganismEquus caballus [Animal]

FamilyDefensin

Tax ID9796

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic Non-ribosomal