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MYP_012087
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Basic Information
Z2
Antimicrobial
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Standard
17 amino acids
C101H193N37O18
Standard
Sequence
RKIIRRIIPIIRRIIKR
Physicochemical Analysis
2213.85 Da
12.00
7.76
7.55
0.4564
-0.02
1.04
-0.41
84.29
183.53
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
943.57
-4.13
37.0
26.0
80.0
156.0
1.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0133906 VERIFIED: YES
Provenance & Taxonomy
synthetic construct based on De novo designed [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-inflammatory
S. paratyphi ATCC 14028
4 μg/mL
MIC
PaperDe novo-designed amphiphilic alpha-helical peptide Z2 exhibits broad-spectrum antimicrobial, anti-biofilm, and anti-inflammatory efficacy in acute Pseudomonas aeruginosa pneumonia.
RECORD: Rec_0216071 VERIFIED: YES
Provenance & Taxonomy
synthetic construct based on De novo designed [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-inflammatory
Klebsiella pneumoniae CMCC46117
4 μg/mL
MIC
PaperDe novo-designed amphiphilic alpha-helical peptide Z2 exhibits broad-spectrum antimicrobial, anti-biofilm, and anti-inflammatory efficacy in acute Pseudomonas aeruginosa pneumonia.
RECORD: Rec_0283519 VERIFIED: YES
Provenance & Taxonomy
synthetic construct based on De novo designed [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-inflammatory
3 strains Acinetobacter baumannii SYP-B4290/B4291/B3819
4-8 μg/mL
MIC
PaperDe novo-designed amphiphilic alpha-helical peptide Z2 exhibits broad-spectrum antimicrobial, anti-biofilm, and anti-inflammatory efficacy in acute Pseudomonas aeruginosa pneumonia.
RECORD: Rec_0345385 VERIFIED: YES
Provenance & Taxonomy
synthetic construct based on De novo designed [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-inflammatory
Pseudomonas aeruginosa ATCC 9027
4 μg/mL
MIC
PaperDe novo-designed amphiphilic alpha-helical peptide Z2 exhibits broad-spectrum antimicrobial, anti-biofilm, and anti-inflammatory efficacy in acute Pseudomonas aeruginosa pneumonia.
RECORD: Rec_0379826 VERIFIED: YES
Provenance & Taxonomy
synthetic construct based on De novo designed [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-inflammatory
4 strains Escherichia coli ATCC 9637 or SYP-B3820/B4288/B4289
2-8 μg/mL
MIC
PaperDe novo-designed amphiphilic alpha-helical peptide Z2 exhibits broad-spectrum antimicrobial, anti-biofilm, and anti-inflammatory efficacy in acute Pseudomonas aeruginosa pneumonia.