Peptide Database

Peptide NameAmolopin-1a antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC363H587N93O106S7

DescriptionStandard

        MFTLKKSMLLLFFLGTINLSLCEQERNADEEDRRDDDEMDVEVEKRFLPMLAGLAANFLPKLFCKITKKC
    

Molecular Weight8174.56 Da

Isoelectric Point (pI)5.04

Net Charge (pH 7.0)-2.51

Net Charge (pH 7.4) -2.80

Charge Density (pH 7.0) -0.0359

GRAVY Index-0.15

Hydrophobic Moment 0.68

Boman Index-0.04

Instability Index32.51

Aliphatic Index 92.00

Aromaticity 0.0857

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3241.79

LogP -23.70

H-bond Donors 113.0

H-bond Acceptors 111.0

Rotatable Bonds 285.0

Heavy Atoms 569.0

Ring Count 8.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0375770 VERIFIED: YES

Provenance & Taxonomy

OrganismAmolops loloensis [Animal]

FamilyBrevinin

Tax ID318551

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Cytolytic Non-hemolytic Non-ribosomal