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MYP_012045
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Basic Information
Ranacyclin-LTb-SN1_2
Antimicrobial
Antimicrobial ▸ Antibacterial
Standard
19 amino acids
C94H150N26O24S2
Standard
Sequence
SALRGCWTKSYPPKPCLGK
Physicochemical Analysis
2092.49 Da
9.70
3.44
3.19
0.1809
-0.63
0.27
-0.09
34.06
46.32
0.1053
6990.00
7115.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
797.42
-7.43
30.0
30.0
63.0
146.0
6.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0163783 VERIFIED: YES
Provenance & Taxonomy
Hylarana spinulosa [Animal]
Ranacyclin
Structure & Mods
Head-to-tail cyclic peptide of the ranacyclin scaffold [Cyclic]
Gene-encoded natural peptide composed of standard L-amino acids [L]
6-16
Bio-Activity Profile
-
PaperH. Wang et al. / Peptides 30 (2009) 273-282. The novel antimicrobial peptides from skin of Chinese broad-folded frog, Hylarana latouchii (Anura:Ranidae) Evidence URLhttps://www.uniprot.org/uniprotkb/E7EKI7/entry
RECORD: Rec_0223234 VERIFIED: YES
Provenance & Taxonomy
Hylarana latouchii [Animal]
Ranacyclin
Structure & Mods
Head-to-tail cyclic peptide of the ranacyclin scaffold [Cyclic]
Gene-encoded natural peptide composed of standard L-amino acids [L]
6-16
Bio-Activity Profile
Antimicrobial Antibacterial
PaperH. Wang et al. / Peptides 30 (2009) 273-282. The novel antimicrobial peptides from skin of Chinese broad-folded frog, Hylarana latouchii (Anura:Ranidae) Evidence URLhttps://www.uniprot.org/uniprotkb/B9W1P3/entry
RECORD: Rec_0314503 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperDADP: the database of anuran defense peptides PMID22467909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22467909/
RECORD: Rec_0379971 VERIFIED: YES
Provenance & Taxonomy
Hylarana spinulosa [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0393050 VERIFIED: NO
Provenance & Taxonomy
Hylarana spinulosa [Animal]
Ranacyclin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID24055160 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24055160/