MYP_012044
Basic Information
Nigrocin-2GRc (Grahamin-2)
Antimicrobial
Antimicrobial Antibacterial Anti-Gram-positive
Antimicrobial Antibiotic activity
Immunology Innate immune defense Host defense peptide Defense peptide
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
Toxicity / Safety Negative safety assay result Non-hemolytic
Standard
67 amino acids
C322H539N87O100S7
Standard
Sequence
MFTMKKSMLLLFFLGTISLSLCEQERNADEEERRDEEVAKMEEIKRGLLSGILGAGKNIVCGLSGLC
Physicochemical Analysis
7453.70 Da
5.05
-2.51
-2.79
-0.0374
0.04
0.57
0.03
57.36
100.45
0.0448
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3042.80
-27.42
109.0
105.0
267.0
516.0
3.0
69.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0078111 VERIFIED: YES
Provenance & Taxonomy
Odorrana grahami [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Defense peptide Antimicrobial Antibiotic Anti-Gram-positive Hemolytic
Staphylococcus aureus (Gram-positive)
RECORD: Rec_0085307 VERIFIED: NO
Provenance & Taxonomy
Odorrana grahami [Animal]
Nigrocin
167935
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0313631 VERIFIED: YES
Provenance & Taxonomy
Odorrana grahami [Animal]
Brevinin
167935
Structure & Mods
gene-encoded linear polypeptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Non-hemolytic Non-ribosomal