Peptide Database

Peptide NameLeucokinin-6

Function Ontology

Anticancer

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Invertebrate neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC42H54N12O13

DescriptionStandard

        QSSFHSWG
    

Molecular Weight934.95 Da

Isoelectric Point (pI)6.74

Net Charge (pH 7.0)-0.15

Net Charge (pH 7.4) -0.41

Charge Density (pH 7.0) -0.0191

GRAVY Index-0.95

Hydrophobic Moment 0.30

Boman Index0.09

Instability Index74.79

Aliphatic Index 0.00

Aromaticity 0.2500

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 415.27

LogP -5.40

H-bond Donors 15.0

H-bond Acceptors 14.0

Rotatable Bonds 27.0

Heavy Atoms 67.0

Ring Count 4.0

Amide Bonds 8.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0014296 VERIFIED: NO

Provenance & Taxonomy

OrganismRhyparobia maderae [Animal]

FamilyLeucokinin

Tax ID36963

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Neuromodulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0071784 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Anticancer

RECORD: Rec_0297444 VERIFIED: NO

Provenance & Taxonomy

OrganismRhyparobia maderae [Animal]

FamilyKinin

Tax ID36963

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Invertebrate neuropeptide

RECORD: Rec_0369642 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyKinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/