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MYP_012039
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Basic Information
DP-107
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV
Antiviral ▸ Anti-Pneumovirus ▸ Anti-RSV
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
38 amino acids
C202H336N60O55
Standard
Sequence
NNLLRAIEAQQHLLQLTVWGIKQLQARILAVERYLKDQ
Physicochemical Analysis
4485.20 Da
9.69
1.85
1.59
0.0487
-0.18
0.49
-0.03
48.47
138.68
0.0526
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1919.31
-14.52
65.0
58.0
156.0
317.0
4.0
45.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0018666 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Hemolytic
Human erythrocytes
40 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/11242518/ PMID11242518 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11242518/
RECORD: Rec_0157687 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Hemolytic
Human erythrocytes
100 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/11242518/ PMID11242518 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11242518/
RECORD: Rec_0162293 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperHIPdb: a database of experimentally validated HIV inhibiting peptides PMID23359817 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23359817/
RECORD: Rec_0260861 VERIFIED: YES
Provenance & Taxonomy
Human immunodeficiency virus 1 [Virus]
11676
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Fusion inhibitor
CEM
0.002 μg/mL
IC50
PaperMethods and compositions for treatment of HIV-1 infection using antiviral compounds in simultaneous or sequential combinations PatentUS6861059
RECORD: Rec_0269958 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 94.7%, E 0.0%, T 0.0%, C 5.3% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Toxic Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
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