Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length144 amino acids

Chemical FormulaC709H1127N187O220S15

DescriptionStandard

        MNLLMLTFVICGLLTQVTKGSFEPQKCWKNNIGCCRRRCLDTERYILLCRNKLSCCISIIMSYEYTRRPPFPVIHLEDITFDYSDIGSFTGSPVSKLSDLVTFDTHGETMTPETNTPETTMPSSETTTSKTTMPPPSQMALTHN
    

Molecular Weight16271.63 Da

Isoelectric Point (pI)6.27

Net Charge (pH 7.0)-1.30

Net Charge (pH 7.4) -1.81

Charge Density (pH 7.0) -0.0090

GRAVY Index-0.23

Hydrophobic Moment 0.60

Boman Index0.02

Instability Index67.61

Aliphatic Index 70.35

Aromaticity 0.0764

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6497.93

LogP -70.69

H-bond Donors 234.0

H-bond Acceptors 237.0

Rotatable Bonds 525.0

Heavy Atoms 1131.0

Ring Count 26.0

Amide Bonds 152.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0339850 VERIFIED: NO

Provenance & Taxonomy

OrganismColobus angolensis palliatus [Animal]

FamilyDefensin

Tax ID336983

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence