Peptide Database

Peptide NameAlloferon (10-13)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length4 amino acids

Chemical FormulaC15H24N6O5

DescriptionStandard

        GVHG
    

Molecular Weight368.39 Da

Isoelectric Point (pI)6.74

Net Charge (pH 7.0)-0.15

Net Charge (pH 7.4) -0.41

Charge Density (pH 7.0) -0.0382

GRAVY Index0.05

Hydrophobic Moment 0.30

Boman Index0.41

Instability Index-18.43

Aliphatic Index 72.50

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 179.30

LogP -2.26

H-bond Donors 6.0

H-bond Acceptors 6.0

Rotatable Bonds 10.0

Heavy Atoms 26.0

Ring Count 1.0

Amide Bonds 3.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0344126 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyAlloferon

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Entry inhibition

Targetinhibition of virus replication in LLC-MK2 cells

Activity540 μM

MethodIC50

Half-LifeMammalian: 30 h; Yeast: >20 h; E. coli: >10 h

RECORD: Rec_0420702 VERIFIED: YES