Peptide Database

Peptide NameOh-defensin (O. hainana defensin; spiders, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length52 amino acids

Chemical FormulaC240H392N62O63S9

DescriptionStandard

        MLCKLSMFGAVLGVPACAIDCLPMGKTGGSCEGGVCGCRKLTFKILWDKKFG
    

Molecular Weight5442.64 Da

Isoelectric Point (pI)8.88

Net Charge (pH 7.0)3.44

Net Charge (pH 7.4) 3.12

Charge Density (pH 7.0) 0.0662

GRAVY Index0.57

Hydrophobic Moment 0.45

Boman Index0.24

Instability Index38.95

Aliphatic Index 82.50

Aromaticity 0.0769

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1956.47

LogP -15.90

H-bond Donors 74.0

H-bond Acceptors 76.0

Rotatable Bonds 182.0

Heavy Atoms 374.0

Ring Count 7.0

Amide Bonds 51.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0394632 VERIFIED: YES

Provenance & Taxonomy

OrganismOrnithoctonus hainana [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

DisulfideDisulfide bond(s) reported

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic

RECORD: Rec_0422428 VERIFIED: YES