Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length68 amino acids

Chemical FormulaC359H577N101O91S9

DescriptionStandard

        MKIHLFLLILLFFEVTILPAKKKYPHYGSMDLRRECIRGNGQCKLECHENEVRIAYCMRPATHCCLQK
    

Molecular Weight8052.63 Da

Isoelectric Point (pI)9.04

Net Charge (pH 7.0)4.80

Net Charge (pH 7.4) 4.27

Charge Density (pH 7.0) 0.0705

GRAVY Index-0.09

Hydrophobic Moment 0.46

Boman Index-0.02

Instability Index66.41

Aliphatic Index 93.24

Aromaticity 0.0882

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3084.53

LogP -20.49

H-bond Donors 113.0

H-bond Acceptors 109.0

Rotatable Bonds 271.0

Heavy Atoms 560.0

Ring Count 13.0

Amide Bonds 71.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0050010 VERIFIED: NO

Provenance & Taxonomy

OrganismTrichechus manatus latirostris [Bacterium]

FamilyDefensin

Tax ID127582

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence