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MYP_011955
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Basic Information
Gageostatin B
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiviral
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
7 amino acids
C38H67N7O12
Standard
Sequence
ELLVDLL
Physicochemical Analysis
813.98 Da
4.05
-2.16
-2.33
-0.3089
1.77
0.51
0.53
-12.90
264.29
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
312.52
0.49
10.0
10.0
27.0
57.0
0.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0405949 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
3-OH-Me-C14,3-OH-C16
None
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID33505362 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33505362/
RECORD: Rec_0408748 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
1423
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
3-β-hydroxy-9,11-dimethyltridecanoic acids
None
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: NUGC-3
10.5 μg/mL
IC50
PMID24492520 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24492520/
RECORD: Rec_0409335 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral Antifungal
Carnobacterium divergens NCFB 2763
1000 μg/mL
MIC
PMID24492520;30973929;30068648;17101680 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24492520/
RECORD: Rec_0410946 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
1423
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
3-β-hydroxy-9,11-dimethyltridecanoic acids
None
Bio-Activity Profile
Antimicrobial Anticancer
NUGC-3
11.8 μg/mL
IC50
PMID24492520 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24492520/
RECORD: Rec_0412797 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral Antifungal
Human breast adenocarcinoma MDA-MB-231
16.1 μg/mL
IC50
PMID24492520;30973929;30068648;17101680 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24492520/
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