‹ ›
MYP_011955
← PREVIOUS NEXT → BACK
Basic Information
Gageostatin B
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiviral
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
7 amino acids
C38H67N7O12
Standard
Sequence
ELLVDLL
Physicochemical Analysis
813.98 Da
4.05
-2.16
-2.33
-0.3089
1.77
0.51
0.53
-12.90
264.29
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
312.52
0.49
10.0
10.0
27.0
57.0
0.0
6.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0160965 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
1423
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
3-β-hydroxy-9,11-dimethyltridecanoic acids
None
Bio-Activity Profile
Antimicrobial Anticancer
HCT 15
11.4 μg/mL
IC50
PMID24492520 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24492520/
RECORD: Rec_0161166 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
1423
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
3-β-hydroxy-11-methyltridecanoic
None
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: PC-3
10.8 μg/mL
IC50
PMID24492520 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24492520/
RECORD: Rec_0166353 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
1423
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
(E)-7,9-dimethylundec-2-enoic acid
None
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: PC-3
10.8 μg/mL
IC50
PMID24492520 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24492520/
RECORD: Rec_0166912 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral Antifungal
Debaryomyces hansenii NCYC 102
256 μg/mL
MIC
PMID24492520;30973929;30068648;17101680 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24492520/
RECORD: Rec_0177537 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
1423
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Lipidation
lipid: 3-beta-hydroxy-9,11-dimethyltridecanoic acid, C15 fatty acid; Gageostatin C: lipid: (E)-7,9-dimethylundec-2-enoic acid, C13 fatty acid chain
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
pathogenic fungi R. solani, B. cinerea and C. acutatum
4-32 μg/mL
MIC
PaperGageostatins A-C, antimicrobial linear lipopeptides from a marine Bacillus subtilis.
FIRST PREV 1 ... 9 10 11 12 13 ... 25 NEXT LAST
Showing 5 records on this page · Page 11 of 25