Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length152 amino acids

Chemical FormulaC752H1176N216O218S8

DescriptionStandard

        MVSKVQFNPRSRTDAIFVHCSATKPEMDIGVETIRMWHKQQGWLDVGYHFIIKRDGTVEEGRPVNVVGSHVKDWNSKSVGVCLVGGIDAKGKFEANFTPAQMNSLRNKLADLKAMYPQAEIKAHHDVAPKACPSFDLQRWLATNELVTSDHG
    

Molecular Weight16987.22 Da

Isoelectric Point (pI)8.46

Net Charge (pH 7.0)2.10

Net Charge (pH 7.4) 1.44

Charge Density (pH 7.0) 0.0138

GRAVY Index-0.39

Hydrophobic Moment 0.57

Boman Index-0.02

Instability Index42.66

Aliphatic Index 75.00

Aromaticity 0.0789

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6963.76

LogP -69.06

H-bond Donors 241.0

H-bond Acceptors 235.0

Rotatable Bonds 562.0

Heavy Atoms 1194.0

Ring Count 30.0

Amide Bonds 164.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0273066 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage EcoDS1 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic