Peptide Database

Peptide NameInterleukin-21

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length133 amino acids

Chemical FormulaC671H1082N204O202S7

DescriptionStandard

        QGQDRHMIRMRQLIDIVDQLKNYVNDLVPEFLPAPEDVETNCEWSAFSCFQKAQLKSANTGNNERIINVSIKKLKRKPPSTNAGRRQKHRLTCPSCDSYEKKPPKEFLERFKSLLQKMIHQHLSSRTHGSEDS
    

Molecular Weight15463.47 Da

Isoelectric Point (pI)9.42

Net Charge (pH 7.0)7.17

Net Charge (pH 7.4) 6.62

Charge Density (pH 7.0) 0.0539

GRAVY Index-0.94

Hydrophobic Moment 0.75

Boman Index-0.25

Instability Index45.21

Aliphatic Index 67.44

Aromaticity 0.0602

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6664.35

LogP -73.56

H-bond Donors 231.0

H-bond Acceptors 221.0

Rotatable Bonds 530.0

Heavy Atoms 1084.0

Ring Count 22.0

Amide Bonds 149.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0336953 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyIL-15/IL-21 family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide42-93; 49-96

Bio-Activity Profile

Function

Cytokine Growth factor IL-15 IL-21 family