Peptide Database

Peptide NameLL-37 KR-12 [K1A]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC68H119N23O16

DescriptionStandard

        ARIVQRIKDFLR
    

Molecular Weight1514.82 Da

Isoelectric Point (pI)11.71

Net Charge (pH 7.0)2.80

Net Charge (pH 7.4) 2.61

Charge Density (pH 7.0) 0.2330

GRAVY Index-0.23

Hydrophobic Moment 0.97

Boman Index-0.34

Instability Index4.78

Aliphatic Index 130.00

Aromaticity 0.0833

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 675.53

LogP -4.55

H-bond Donors 25.0

H-bond Acceptors 19.0

Rotatable Bonds 53.0

Heavy Atoms 107.0

Ring Count 1.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0390657 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetEscherichia coli K-12

Activity63

MethodMIC

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