Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC541H872N146O166S3

DescriptionStandard

        PDLTGHEKFGLGNVKYNISRIHVTAVELPSASISLLPGTGIKLVIGNASLTIDMNWNIRTWMFKDSGRGTVHISKVFVTAVFSTPLDNTGPTSISLTSCQTTSGDIDIKLNGKS
    

Molecular Weight12173.78 Da

Isoelectric Point (pI)8.98

Net Charge (pH 7.0)2.21

Net Charge (pH 7.4) 1.97

Charge Density (pH 7.0) 0.0194

GRAVY Index0.04

Hydrophobic Moment 0.54

Boman Index0.14

Instability Index17.18

Aliphatic Index 95.70

Aromaticity 0.0614

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4977.26

LogP -56.91

H-bond Donors 176.0

H-bond Acceptors 174.0

Rotatable Bonds 401.0

Heavy Atoms 856.0

Ring Count 17.0

Amide Bonds 121.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0087168 VERIFIED: NO

Provenance & Taxonomy

OrganismMyiagra hebetior [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria