Peptide Database

Peptide NameProtegrin 1 / Neutrophil peptide 1 [C6A][C8A][C13A][C15A]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC88H150N36O20

DescriptionStandard

        RGGRLAYARRRFAVAVGR
    

Molecular Weight2032.36 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)5.76

Net Charge (pH 7.4) 5.55

Charge Density (pH 7.0) 0.3199

GRAVY Index-0.41

Hydrophobic Moment 0.41

Boman Index-0.37

Instability Index83.67

Aliphatic Index 76.11

Aromaticity 0.1111

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 949.65

LogP -10.26

H-bond Donors 38.0

H-bond Acceptors 26.0

Rotatable Bonds 67.0

Heavy Atoms 144.0

Ring Count 2.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0387680 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Toxic Hemolytic

RECORD: Rec_0406149 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetNeisseria gonorrhoeae F62

Activity10.0

MethodMIC

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