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MYP_011893
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Basic Information
Protegrin 1 / Neutrophil peptide 1 [C6A][C8A][C13A][C15A]
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
18 amino acids
C88H150N36O20
Standard
Sequence
RGGRLAYARRRFAVAVGR
Physicochemical Analysis
2032.36 Da
12.00
5.76
5.55
0.3199
-0.41
0.41
-0.37
83.67
76.11
0.1111
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
949.65
-10.26
38.0
26.0
67.0
144.0
2.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0003790 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Neisseria gonorrhoeae FA19
223.7
MIC
PMID10795591;9009324 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10795591/
RECORD: Rec_0029465 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
methicillin-resistant Staphylococcus aureus
16 μg/mL
MIC
PMID10931444 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10931444/
RECORD: Rec_0113708 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
80 μg/mL
Hemolysis
PMID10795591;9009324 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10795591/
RECORD: Rec_0193967 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa
64 μg/mL
MIC
PMID10931444 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10931444/
RECORD: Rec_0371342 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
80 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/10795591/ PMID10795591 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10795591/
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