Peptide Database

Peptide NameBrevinin-2RTb antimicrobial peptide (Frogs, amphibians, animals)

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC354H580N90O115S5

DescriptionStandard

        MFTSKKSLLVLFFLGTISLSFCEEERNADEDDGEMTEEVKRGILDTLKEFGKTAAKGIAQSLLSTASCKLAKTC
    

Molecular Weight8097.25 Da

Isoelectric Point (pI)5.05

Net Charge (pH 7.0)-2.51

Net Charge (pH 7.4) -2.80

Charge Density (pH 7.0) -0.0339

GRAVY Index-0.08

Hydrophobic Moment 0.71

Boman Index0.02

Instability Index33.15

Aliphatic Index 84.46

Aromaticity 0.0676

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3336.58

LogP -34.39

H-bond Donors 120.0

H-bond Acceptors 118.0

Rotatable Bonds 285.0

Heavy Atoms 564.0

Ring Count 5.0

Amide Bonds 75.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0024317 VERIFIED: YES

Provenance & Taxonomy

OrganismAmolops ricketti [Animal]

FamilyBrevinin

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0162836 VERIFIED: YES