Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC357H571N107O98S11

DescriptionStandard

        MVTGKLFKDISTPVLGCRCQAGLEYSQPFPGGDFAVCEPCWLGRGKCRRICTEDEKVVGNCKMNFFCCRRRIR
    

Molecular Weight8282.73 Da

Isoelectric Point (pI)8.99

Net Charge (pH 7.0)5.42

Net Charge (pH 7.4) 5.05

Charge Density (pH 7.0) 0.0742

GRAVY Index-0.22

Hydrophobic Moment 0.61

Boman Index-0.09

Instability Index51.99

Aliphatic Index 60.00

Aromaticity 0.0959

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3319.29

LogP -33.17

H-bond Donors 126.0

H-bond Acceptors 115.0

Rotatable Bonds 274.0

Heavy Atoms 573.0

Ring Count 12.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0031983 VERIFIED: NO

Provenance & Taxonomy

OrganismVulpes vulpes [Bacterium]

FamilyDefensin

Tax ID9627

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence