Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length196 amino acids

Chemical FormulaC999H1570N270O263S8

DescriptionStandard

        PMAHEPMLLLAVTEFVANSAAFTYFTAGALRRNISSDMLPQQFPLQLRTKSMEVFSPQLQERYPDRPMELHLWARRQPLLSCHPDALHGTLFSSAEAFVVLPNGTRVPAFLLNIDANVTGKPTITRNRLGGTVRLTGLVPDPELALPAPWTPLPALFWAQTLPVPQVKRLETLLKFGLWLFGVPRANSKCCPRPVP
    

Molecular Weight21827.32 Da

Isoelectric Point (pI)9.73

Net Charge (pH 7.0)6.30

Net Charge (pH 7.4) 5.97

Charge Density (pH 7.0) 0.0321

GRAVY Index0.02

Hydrophobic Moment 0.54

Boman Index0.10

Instability Index56.54

Aliphatic Index 94.08

Aromaticity 0.0867

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8333.24

LogP -98.76

H-bond Donors 285.0

H-bond Acceptors 281.0

Rotatable Bonds 678.0

Heavy Atoms 1540.0

Ring Count 49.0

Amide Bonds 210.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0226684 VERIFIED: NO

Provenance & Taxonomy

OrganismVireo altiloquus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria