Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC741H1160N216O219S7

DescriptionStandard

        MAKVQFTKRQETSQIFVHCSATKATMDVGVREIRQWHKEQGWLDVGYHFIIRRDGTVEAGRDQDAVGSHVKGYNSTSVGVCLVGGIDAKGNPEANFTPAQMQALRSLLVELKVQYTGAVLMAHHDVAPKACPSFDLKRWWEKNELVTSDHG
    

Molecular Weight16822.91 Da

Isoelectric Point (pI)7.79

Net Charge (pH 7.0)1.10

Net Charge (pH 7.4) 0.45

Charge Density (pH 7.0) 0.0073

GRAVY Index-0.38

Hydrophobic Moment 0.75

Boman Index-0.02

Instability Index38.19

Aliphatic Index 75.50

Aromaticity 0.0795

Extinction Coeff. Reduced 26470.00

Extinction Coeff. Oxidized 26595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7011.35

LogP -71.89

H-bond Donors 246.0

H-bond Acceptors 234.0

Rotatable Bonds 560.0

Heavy Atoms 1183.0

Ring Count 27.0

Amide Bonds 163.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0272781 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella phage KP32 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic