Peptide Database

Peptide NamePhrC signal peptide

Function Ontology

Annotation / Sequence feature ▸ Signal peptide

Biotechnology / Production and expression ▸ Secretory enzyme production ▸ Cutinase secretion

Biotechnology / Production and expression ▸ Secretory expression optimization

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC118H197N29O31S2

DescriptionStandard

        MLKSKLFVICLAAAAIFTAAGVSANA
    

Molecular Weight2582.13 Da

Isoelectric Point (pI)9.31

Net Charge (pH 7.0)1.49

Net Charge (pH 7.4) 1.26

Charge Density (pH 7.0) 0.0573

GRAVY Index1.51

Hydrophobic Moment 0.18

Boman Index0.49

Instability Index10.49

Aliphatic Index 128.08

Aromaticity 0.0769

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 946.64

LogP -7.48

H-bond Donors 34.0

H-bond Acceptors 35.0

Rotatable Bonds 84.0

Heavy Atoms 180.0

Ring Count 2.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0206020 VERIFIED: YES

Provenance & Taxonomy

OrganismBacillus subtilis [Bacterium]

FamilySec signal peptide

Tax ID1423

Structure & Mods

Configlinear signal peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Protein secretion signal peptide Secretory expression optimization Cutinase secretion

TargetBacillus subtilis TEB1030

Activity2.0 U/mL

MethodCutinase activity assay

PaperBrockmeier U, Caspers M, Freudl R, et al. Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria[J]. Journal of Molecular Biology, 2006, 362(3): 393-402. PMID16930615 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16930615/