Peptide Database

Peptide NameKalata B1 [T16Y]

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC122H189N35O40S6

DescriptionStandard

        GLPVCGETCVGGTCNYPGCTCSWPVCTRN
    

Molecular Weight2978.41 Da

Isoelectric Point (pI)5.96

Net Charge (pH 7.0)-0.30

Net Charge (pH 7.4) -0.59

Charge Density (pH 7.0) -0.0103

GRAVY Index0.13

Hydrophobic Moment 0.25

Boman Index0.16

Instability Index53.77

Aliphatic Index 43.45

Aromaticity 0.0690

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1174.30

LogP -16.69

H-bond Donors 46.0

H-bond Acceptors 46.0

Rotatable Bonds 85.0

Heavy Atoms 203.0

Ring Count 6.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0062628 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

FamilyCyclotide

Tax ID32630

Structure & Mods

Configside-chain cyclized/stapled peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer

Target(Not active up to 60 μM)

RECORD: Rec_0077266 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

FamilyCyclotide

Tax ID32630

Structure & Mods

Configside-chain cyclized/stapled peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetMM96L (Not active up to 60 μM)

RECORD: Rec_0201344 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

FamilyCyclotide

Tax ID32630

Structure & Mods

Configside-chain cyclized/stapled peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetTumor cells: HeLa (Not active up to 60 μM)

RECORD: Rec_0284219 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

FamilyCyclotide

Tax ID32630

Structure & Mods

Configside-chain cyclized/stapled peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer Hemolytic

TargetμM

Activity50 μM

MethodHemolysis

RECORD: Rec_0401888 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

FamilyCyclotide

Tax ID32630

Structure & Mods

Configside-chain cyclized/stapled peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer Cytotoxic

TargetμM

Activity60 μM

MethodCytotoxicity