Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length485 amino acids

Chemical FormulaC2390H3715N601O693S23

DescriptionStandard

        MLLSDIMTRGAGEMFPSIIALLTLISVSCGQGPGLQVILTNKGLQYGKHVGAGWIQDRLNNITFPDISGKVLGAIHFTLTGITITKCDFPEPSVEFYQDATGFKTSMSGLSVALAGWWKTQFGIIHDGGSFNLAIFSVDVTSVVGLGKDADGRLSVTSVSCDANVGDVDMQFYGGASAIFKPFVKYFKGRIRGEIQRHICPKLEEAIVMIEEQLQAMNVSFDVDQDVTLEFPLTSLPVVNASSMNLGLKGEFYSIKHHEEPPFKPQLFAVPEQQGYMLSVGLSEFTLNSASYGYYLAGLFQALINDSVIPPSLHMHLNTSEMGPFIPQLPKMFPDLLMNLQVYARDAPLFSFQPGAIKLDFHGAVKAFAIQPNHTQTPLFNLNVDSDFSGKVWVADGKLKASMGMNNLTVTLASSEVGPFKTDAIEKVAKLGSTVFMAKVNEILGKGADLPRMKQVVPVNTVLQMDMGFIAIFSDAQVLTDGDFD
    

Molecular Weight52693.17 Da

Isoelectric Point (pI)5.23

Net Charge (pH 7.0)-12.62

Net Charge (pH 7.4) -13.50

Charge Density (pH 7.0) -0.0260

GRAVY Index0.16

Hydrophobic Moment 0.67

Boman Index0.19

Instability Index32.93

Aliphatic Index 93.05

Aromaticity 0.0969

Extinction Coeff. Reduced 36900.00

Extinction Coeff. Oxidized 37150.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0341454 VERIFIED: NO

Provenance & Taxonomy

OrganismLarimichthys crocea (Large yellow croaker) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria