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MYP_011814
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-III Inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Lipase inhibition
Enzyme modulation ▸ Enzyme inhibition ▸ Renin inhibition ▸ Renin inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
2 amino acids
C13H18N2O4
Standard
Sequence
TF
Physicochemical Analysis
266.29 Da
5.18
-0.60
-0.79
-0.3009
1.05
0.60
0.57
66.70
0.00
0.5000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
112.65
-0.49
4.0
4.0
6.0
19.0
1.0
1.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0126892 VERIFIED: YES
Provenance & Taxonomy
Camelus dromedarius [Animal]
beta-Casein-derived
9838
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
18 μM
IC50
PaperRelease of angiotensin converting enzyme-inhibitory peptides during in vitro gastro-intestinal digestion of camel milk | Tagliazucchi, D. et al. | DOI: 10.1016/j.idairyj.2016.01.009 Evidence URLhttps://www.uniprot.org/uniprotkb/Q9TVD0/entry
RECORD: Rec_0193270 VERIFIED: YES
Provenance & Taxonomy
Triticum aestivum [Plant]
Angiotensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-converting enzyme
17.8 μM
IC50
RECORD: Rec_0198233 VERIFIED: YES
Provenance & Taxonomy
Triticum aestivum [Plant]
ACE-inhibitory peptide
4565
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
18 μM
IC50
PaperAngiotensin I Converting Enzyme Inhibitory Peptides Produced by Autolysis Reactions from Wheat Bran PMID19572648 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19572648/
RECORD: Rec_0213356 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Metabolic Syndrome Pancreatic lipase inhibitory
Pancreatic lipase
751.0
IC50
PaperWang X., Ai X., Zhu Z., Zhang M., Pan F., Yang Z., Wang O., Zhao L., Zhao L.. Pancreatic lipase inhibitory effects of peptides derived from sesame proteins: In silico and in vitro analyses. Int. J. Biol. Macromol., 222, 1531-1537, 2022.
RECORD: Rec_0264923 VERIFIED: YES
Provenance & Taxonomy
Brassica napus [Plant]
ACE-inhibitory peptide
3708
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
Spontaneously hypertensive rat (SHR)
12 mmHg
SBP decrease
PaperGlycinyl-Histidinyl-Serine (GHS), a Novel Rapeseed Protein-Derived Peptide Has Blood Pressure-Lowering Effect in Spontaneously Hypertensive Rats PMID23919612 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23919612/
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