Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length50 amino acids

Chemical FormulaC261H424N70O71S2

DescriptionStandard

        MAKLDDFDLDIVVKKQDNIVQPNITSKSLLYPGLHHRHLNVLNAKFLCIL
    

Molecular Weight5742.71 Da

Isoelectric Point (pI)7.95

Net Charge (pH 7.0)0.75

Net Charge (pH 7.4) 0.36

Charge Density (pH 7.0) 0.0150

GRAVY Index0.07

Hydrophobic Moment 0.47

Boman Index0.08

Instability Index47.74

Aliphatic Index 128.60

Aromaticity 0.0600

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2275.64

LogP -16.25

H-bond Donors 76.0

H-bond Acceptors 77.0

Rotatable Bonds 194.0

Heavy Atoms 404.0

Ring Count 8.0

Amide Bonds 55.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0327892 VERIFIED: NO

Provenance & Taxonomy

OrganismGeobacillus kaustophilus [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence