Peptide Database

Peptide NameUrotoxin (α-KTx 6.21)

Function Ontology

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC161H267N51O51S9

DescriptionStandard

        GDIKCSGTRQCWGPCKKQTTCTNSKCMNGKCKCYGCV
    

Molecular Weight4021.74 Da

Isoelectric Point (pI)9.06

Net Charge (pH 7.0)5.67

Net Charge (pH 7.4) 5.34

Charge Density (pH 7.0) 0.1534

GRAVY Index-0.68

Hydrophobic Moment 0.44

Boman Index-0.20

Instability Index19.13

Aliphatic Index 18.38

Aromaticity 0.0541

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1687.21

LogP -24.62

H-bond Donors 67.0

H-bond Acceptors 66.0

Rotatable Bonds 136.0

Heavy Atoms 272.0

Ring Count 4.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0431962 VERIFIED: YES

Provenance & Taxonomy

OrganismUrodacus yaschenkoi [Animal]

Familyα-KTx-6

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermC-terminal amidation (Val37-NH2)

Other ModsC-terminal amidation

Bio-Activity Profile

Function

Potassium channel blocker; Ion channel inhibitor; Toxin

Targethuman hELK2 potassium channel

MethodElectrophysiological potassium-channel inhibition assay

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