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MYP_011787
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Basic Information
CM4
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
35 amino acids
C172H290N50O44
Standard
Sequence
RWKIFKKIEKVGQNIRDGIVKAGPAVAVVGQAATI
Physicochemical Analysis
3762.45 Da
10.56
4.76
4.55
0.1360
0.13
0.82
0.08
34.59
111.43
0.0571
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1537.72
-12.21
53.0
49.0
129.0
266.0
4.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0317405 VERIFIED: YES
Provenance & Taxonomy
Bombyx mori [Animal]
Cecropin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperPubMed PMID: 3318666 PMID3318666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3318666/
RECORD: Rec_0322748 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Toxic Hemolytic Cytotoxic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0329819 VERIFIED: YES
Provenance & Taxonomy
Bombyx mori [Animal]
7091
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
A. niger
4 μM
MIC
PaperSeparation, purification of antibacterial CM4 and the research of the structure and character
RECORD: Rec_0330017 VERIFIED: YES
Provenance & Taxonomy
Bombyx mori [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Gram-negative and Gram-positive bacteria
PMID3318666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3318666/
RECORD: Rec_0368110 VERIFIED: YES
Provenance & Taxonomy
Bombyx mori [Animal]
7091
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
P. chrysogenum
22 μM
MIC
PaperSeparation, purification of antibacterial CM4 and the research of the structure and character
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