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MYP_011787
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Basic Information
CM4
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
35 amino acids
C172H290N50O44
Standard
Sequence
RWKIFKKIEKVGQNIRDGIVKAGPAVAVVGQAATI
Physicochemical Analysis
3762.45 Da
10.56
4.76
4.55
0.1360
0.13
0.82
0.08
34.59
111.43
0.0571
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1537.72
-12.21
53.0
49.0
129.0
266.0
4.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0160948 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://patents.google.com/patent/US20080170991A1/en PatentUS 2008/0170991 A1
RECORD: Rec_0162918 VERIFIED: YES
Provenance & Taxonomy
Bombyx mori [Animal]
7091
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Salmonella spp
14-16 μM
MIC
PaperSeparation, purification of antibacterial CM4 and the research of the structure and character
RECORD: Rec_0167922 VERIFIED: YES
Provenance & Taxonomy
Bombyx mori [Animal]
7091
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
P. chrysogenum
18 μM
MIC
PaperSeparation, purification of antibacterial CM4 and the research of the structure and character
RECORD: Rec_0216155 VERIFIED: YES
Provenance & Taxonomy
Bombyx mori [Animal]
7091
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Salmonella spp
14 μM
MIC
PaperSeparation, purification of antibacterial CM4 and the research of the structure and character
RECORD: Rec_0277889 VERIFIED: NO
Provenance & Taxonomy
Bombyx mori [Animal]
Cecropin
7091
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperAnnu Rev Microbiol. 1987;41:103-26. | http://www.ncbi.nlm.nih.gov/pubmed/3318666 PMID3318666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3318666/
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