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MYP_011787
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Basic Information
CM4
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
35 amino acids
C172H290N50O44
Standard
Sequence
RWKIFKKIEKVGQNIRDGIVKAGPAVAVVGQAATI
Physicochemical Analysis
3762.45 Da
10.56
4.76
4.55
0.1360
0.13
0.82
0.08
34.59
111.43
0.0571
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1537.72
-12.21
53.0
49.0
129.0
266.0
4.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0012627 VERIFIED: YES
Provenance & Taxonomy
Bombyx mori [Animal]
7091
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Escherichia coli K12D31
12 μM
MIC
PaperSeparation, purification of antibacterial CM4 and the research of the structure and character
RECORD: Rec_0047123 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Cytotoxic
Human erythrocytes
400 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/20493915/ PMID20493915 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20493915/
RECORD: Rec_0050959 VERIFIED: YES
Provenance & Taxonomy
Bombyx mori [Animal]
7091
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Pseudomonas aeruginosa
20 μM
MIC
PaperSeparation, purification of antibacterial CM4 and the research of the structure and character
RECORD: Rec_0067488 VERIFIED: NO
Provenance & Taxonomy
Bombyx mori [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Lytic
RECORD: Rec_0154196 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Cytotoxic
Human erythrocytes
200 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/20493915/ PMID20493915 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20493915/
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