Peptide Database

Peptide NameG4-14A gliadin (p62-p75; E65 and A70)

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC74H111N17O21

DescriptionStandard

        PQPELPYPQPQLPA
    

Molecular Weight1574.77 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.04

Net Charge (pH 7.4) -1.10

Charge Density (pH 7.0) -0.0743

GRAVY Index-1.11

Hydrophobic Moment 0.16

Boman Index0.03

Instability Index140.57

Aliphatic Index 62.86

Aromaticity 0.0714

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 570.48

LogP -3.62

H-bond Donors 15.0

H-bond Acceptors 20.0

Rotatable Bonds 40.0

Heavy Atoms 112.0

Ring Count 7.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0409371 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDeamidation; Reported substitutions/positions: G4; Reported substitutions/positions: E65; Reported substitutions/positions: A70; Reported substitution variant

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman intestinal T cells / HLA-DQ2

MethodIntestinal T-cell assay