Peptide Database

Peptide NameTL1A

Function Ontology

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length251 amino acids

Chemical FormulaC1260H1953N333O369S13

DescriptionStandard

        MAEDLGLSFGETASVEMLPEHGSCRPKARSSSARWALTCCLVLLPFLAGLTTYLLVSQLRAQGEACVQFQALKGQEFAPSHQQVYAPLRADGDKPRAHLTVVRQTPTQHFKNQFPALHWEHELGLAFTKNRMNYTNKFLLIPESGDYFIYSQVTFRGMTSECSEIRQAGRPNKPDSITVVITKVTDSYPEPTQLLMGTKSVCEVGSNWFQPIYLGAMFSLQEGDKLMVNVSDISLVDYTKEDKTFFGAFLL
    

Molecular Weight28086.84 Da

Isoelectric Point (pI)6.31

Net Charge (pH 7.0)-2.00

Net Charge (pH 7.4) -2.67

Charge Density (pH 7.0) -0.0080

GRAVY Index-0.17

Hydrophobic Moment 0.59

Boman Index0.06

Instability Index36.35

Aliphatic Index 80.04

Aromaticity 0.1036

Extinction Coeff. Reduced 28420.00

Extinction Coeff. Oxidized 28795.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0018388 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidereported in GtoPdb PTM annotation

Other ModsPredicted N-linked glycosylation of asparagine residues at positions 133 and 229; disulphide bond formation between cysteine residues at positions 162 and 202

Bio-Activity Profile

Function

Immunomodulatory Signaling peptide

Targetdeath receptor 3 (Human)