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MYP_011751
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Basic Information
Caerin 1.7
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiviral
Standard
24 amino acids
C120H199N31O28
Standard
Sequence
GLFKVLGSVAKHLLPHVAPVIAEK
Physicochemical Analysis
2524.05 Da
9.70
1.93
1.62
0.0806
0.76
0.59
0.33
23.86
142.08
0.0417
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
907.99
-3.84
30.0
32.0
81.0
179.0
5.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0255480 VERIFIED: YES
Provenance & Taxonomy
Litoria xanthomera [Animal]
Caerin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer
PaperM.A. Apponyi et al. / Peptides 25 (2004) 1035-1054. Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance PMID15203252 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15203252/
RECORD: Rec_0300128 VERIFIED: YES
Provenance & Taxonomy
Amphibia [Animal]
Caerin
8292
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID9230483 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9230483/
RECORD: Rec_0311831 VERIFIED: YES
Provenance & Taxonomy
Litoria xanthomera [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0331852 VERIFIED: NO
Provenance & Taxonomy
Amphibia [Animal]
Caerin
8292
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0341396 VERIFIED: YES
Provenance & Taxonomy
Litoria xanthomera [Animal]
Caerin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperCancerPPD2 curated year-page record (1996–2000); partial row recovered from visible page.
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