Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC742H1164N216O217S7

DescriptionStandard

        MPKVQFTKRKETSQIFVHCSATKPSMDIGVREIAQWHKEQGWLAIGYHFVIRRDGTVEAGRDQDAVGSHVKGYNSTSVGVCLVGGIDAKGNHEANFTPAQMQSLRSLLVELKVQYSGAVLMAHHDVAPKACPSFDLKRWWEKNELVTSDRG
    

Molecular Weight16806.95 Da

Isoelectric Point (pI)8.81

Net Charge (pH 7.0)3.10

Net Charge (pH 7.4) 2.44

Charge Density (pH 7.0) 0.0205

GRAVY Index-0.39

Hydrophobic Moment 0.65

Boman Index-0.02

Instability Index41.06

Aliphatic Index 75.50

Aromaticity 0.0795

Extinction Coeff. Reduced 26470.00

Extinction Coeff. Oxidized 26595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6968.42

LogP -71.41

H-bond Donors 245.0

H-bond Acceptors 234.0

Rotatable Bonds 560.0

Heavy Atoms 1182.0

Ring Count 28.0

Amide Bonds 162.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0375003 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella phage Kp_Pokalde_002 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic