Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length69 amino acids

Chemical FormulaC348H572N94O93S8

DescriptionStandard

        MKAFLLTLAALVLLSQVTSGSAEKCWNLRGSCREKCIKNEKLYIFCTSGKLCCLKPKFQPNMLQRSVQF
    

Molecular Weight7817.36 Da

Isoelectric Point (pI)9.54

Net Charge (pH 7.0)7.44

Net Charge (pH 7.4) 7.12

Charge Density (pH 7.0) 0.1078

GRAVY Index0.11

Hydrophobic Moment 0.41

Boman Index0.03

Instability Index34.89

Aliphatic Index 91.88

Aromaticity 0.0870

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3050.02

LogP -27.15

H-bond Donors 112.0

H-bond Acceptors 109.0

Rotatable Bonds 268.0

Heavy Atoms 543.0

Ring Count 9.0

Amide Bonds 75.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0319248 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris (Dog) [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

RECORD: Rec_0399061 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyDefensin

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence