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MYP_011699
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Basic Information
Ib-AMP4
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
20 amino acids
C108H160N42O23S4
Standard
Sequence
QWGRRCCGWGPGRRYCRRWC
Physicochemical Analysis
2542.95 Da
10.66
5.72
5.46
0.2860
-1.39
0.69
-0.51
116.09
0.00
0.2000
17990.00
18240.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1089.52
-10.67
47.0
33.0
77.0
177.0
8.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0081749 VERIFIED: YES
Provenance & Taxonomy
Impatiens balsamina [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Xanthomonas campestris
6 μg/mL
IC50
PaperPubMed PMID: 9305910 | PubMed PMID: 9454588 PMID9305910;9454588 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9305910/
RECORD: Rec_0086482 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Impatiens balsamina [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Pyroglutamate
6-16
Bio-Activity Profile
Antimicrobial Antifungal
P. pastoris
5 μM
IC50
PaperA Novel Family of Small Cysteine-rich Antimicrobial Peptides from Seed of Impatiens balsamina Is Derived from a Single Precursor Protein
RECORD: Rec_0097592 VERIFIED: YES
Provenance & Taxonomy
Impatiens balsamina [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Micrococcus luteus
5 μg/mL
IC50
PaperPubMed PMID: 9305910 | PubMed PMID: 9454588 PMID9305910;9454588 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9305910/
RECORD: Rec_0098038 VERIFIED: YES
Provenance & Taxonomy
Impatiens balsamina [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Streptococcus pneumoniae 49619
20 μg/mL
MIC
PMID30986507 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30986507/
RECORD: Rec_0100448 VERIFIED: YES
Provenance & Taxonomy
Impatiens balsamina [Plant]
Impatiens family
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Pyroglutamate
6-16; 7-20
N-terminal pyroglutamate
Bio-Activity Profile
Antimicrobial Antibacterial Hemolytic Cytotoxic Antifungal Anti-Gram-positive
Staphylococcus aureus
4月8日 μg/mL
MIC
PaperPubMed PMID 3713064 | PubMed PMID 2371306 | PubMed PMID 4000000 | Fan X et al., 2013 PMID3713064;2371306;4000000;37130642;37130;64000 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3713064/
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