Peptide Database

Peptide NameTheta defensin subunit A (BTD-a) (BTD-1 subunit 1) (BTD-3) (BTD-4 subunit 1) (BTD-7 subunit 1)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC354H571N107O105S6

DescriptionStandard

        MRTFALLTAMLLLVALHAQAEARQARADEAAAQQQPGADDQGMAHSFTWPENAALPLSESAKGLRCVCTRGFCRLL
    

Molecular Weight8198.36 Da

Isoelectric Point (pI)6.70

Net Charge (pH 7.0)-0.34

Net Charge (pH 7.4) -0.71

Charge Density (pH 7.0) -0.0045

GRAVY Index0.02

Hydrophobic Moment 0.59

Boman Index0.05

Instability Index29.30

Aliphatic Index 85.13

Aromaticity 0.0526

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3394.36

LogP -36.07

H-bond Donors 120.0

H-bond Acceptors 113.0

Rotatable Bonds 269.0

Heavy Atoms 572.0

Ring Count 10.0

Amide Bonds 82.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0078708 VERIFIED: YES

Provenance & Taxonomy

OrganismPapio anubis [Animal]

FamilyAlpha-defensin; Defensin

Tax ID9555

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus (Gram-positive)

RECORD: Rec_0218850 VERIFIED: YES

Provenance & Taxonomy

OrganismPapio anubis [Animal]

FamilyAlpha-defensin; Defensin

Tax ID9555

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetEscherichia coli (Gram-negative)

RECORD: Rec_0350403 VERIFIED: YES

Provenance & Taxonomy

OrganismPapio anubis [Animal]

FamilyAlpha-defensin; Defensin

Tax ID9555

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetCandida albicans