Peptide Database

Peptide Namehuman LL-29

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC145H241N39O36

DescriptionStandard

        LGNFFRKAKEKIGGELKKIGQKIKDFL
    

Molecular Weight3106.70 Da

Isoelectric Point (pI)10.12

Net Charge (pH 7.0)4.76

Net Charge (pH 7.4) 4.54

Charge Density (pH 7.0) 0.1763

GRAVY Index-0.59

Hydrophobic Moment 0.77

Boman Index-0.13

Instability Index-15.82

Aliphatic Index 90.37

Aromaticity 0.1111

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1262.04

LogP -7.94

H-bond Donors 43.0

H-bond Acceptors 41.0

Rotatable Bonds 116.0

Heavy Atoms 220.0

Ring Count 3.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0238315 VERIFIED: YES

Provenance & Taxonomy

OrganismColobus angolensis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)