Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length137 amino acids

Chemical FormulaC664H1060N188O215S11

DescriptionStandard

        MPGSTTYYFPRSMRLLLLALPALALLPQVIPAYSGEKKCLNSSGNCRKNCEDGETIQDTCKNHRVCCVPIMRANKPKASVRVSWTTEETTTMEYDLNSEFMDELNTEIDSEFVDVRHEERTGLRGGWRALSLESESS
    

Molecular Weight15469.37 Da

Isoelectric Point (pI)5.24

Net Charge (pH 7.0)-4.35

Net Charge (pH 7.4) -4.80

Charge Density (pH 7.0) -0.0317

GRAVY Index-0.51

Hydrophobic Moment 0.76

Boman Index-0.10

Instability Index48.79

Aliphatic Index 71.17

Aromaticity 0.0657

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6523.70

LogP -72.79

H-bond Donors 234.0

H-bond Acceptors 224.0

Rotatable Bonds 514.0

Heavy Atoms 1078.0

Ring Count 20.0

Amide Bonds 145.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0178605 VERIFIED: NO

Provenance & Taxonomy

OrganismPeromyscus maniculatus bairdii [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin